# cancer

**URL:** https://discourse.datamethods.org/c/topical/ca/57.md

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## [About the cancer category](https://discourse.datamethods.org/t/about-the-cancer-category/80)

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**Author:** [@f2harrell](https://discourse.datamethods.org/u/f2harrell)\
**Replies:** 0

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Cancer research and clinical decision making involving data

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## [Design ideas for non-inferiority trials were event rates are low](https://discourse.datamethods.org/t/design-ideas-for-non-inferiority-trials-were-event-rates-are-low/6795)

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**Author:** [@S\_Chakraborty](https://discourse.datamethods.org/u/S_Chakraborty)\
**Replies:** 8\
**Last updated:** [May 21, 2023, 9:11pm UTC](https://discourse.datamethods.org/t/design-ideas-for-non-inferiority-trials-were-event-rates-are-low/6795 "2023-05-21T21:11:49Z")

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In oncology, we often encounter situations where the event rate is quite low and de-escalation trials are planned to reduce toxicity and potentially improve QoL. In cancer sites with a large patient population, non-infer…