# Guidance of analysis of longitudinal patient reported outcomes w.r.t Joint models

**URL:** <https://discourse.datamethods.org/t/guidance-of-analysis-of-longitudinal-patient-reported-outcomes-w-r-t-joint-models/7034>\
**Category:** modeling strategy\
**Tags:** rct, longitudinal, interpretation\
**Created:** [August 27, 2023, 6:08pm UTC](https://discourse.datamethods.org/t/guidance-of-analysis-of-longitudinal-patient-reported-outcomes-w-r-t-joint-models/7034 "2023-08-27T18:08:55Z")\
**Posts on this page:** 1\
**Showing post:** 3

<div class="post-metadata">

**Author:** ![S\_Chakraborty](https://discourse.datamethods.org/user_avatar/discourse.datamethods.org/s_chakraborty/32/1777_2.png) [@S\_Chakraborty](https://discourse.datamethods.org/u/S_Chakraborty)\
**Post date:** [August 28, 2023, 2:00am UTC](https://discourse.datamethods.org/t/guidance-of-analysis-of-longitudinal-patient-reported-outcomes-w-r-t-joint-models/7034/3 "2023-08-28T02:00:42Z")

</div>

Is there any guidance on the use of multi-state transition models w.r.t patient reported outcomes ? I am curious as most of the patient reported outcomes have multiple scales with scores for each scale (e.g EORTC QLQ C30 provides scores for 5 functional scales, 7 symptom scales and 1 global health / quality of life scale). The scores are standardized such that they range between 0 - 100 where 100 means the worst symptom or the best functional outcome. I would like to thank you for the discussion we had on a related topic [here](https://discourse.datamethods.org/t/design-ideas-for-non-inferiority-trials-were-event-rates-are-low/6795/3) but will a multi-state transition model be a better choice for trial design and analysis ?

---

_[View the full topic](https://discourse.datamethods.org/t/guidance-of-analysis-of-longitudinal-patient-reported-outcomes-w-r-t-joint-models/7034)._