# Quality of remdesivir trials

**URL:** <https://discourse.datamethods.org/t/quality-of-remdesivir-trials/3881>\
**Category:** journal club\
**Tags:** rct, design, interpretation\
**Created:** [October 29, 2020, 12:24pm UTC](https://discourse.datamethods.org/t/quality-of-remdesivir-trials/3881 "2020-10-29T12:24:17Z")\
**Posts on this page:** 1\
**Showing post:** 29

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**Author:** ![Pavlos\_Msaouel](https://discourse.datamethods.org/user_avatar/discourse.datamethods.org/pavlos_msaouel/32/739_2.png) [@Pavlos\_Msaouel](https://discourse.datamethods.org/u/Pavlos_Msaouel)\
**Post date:** [November 12, 2020, 11:01pm UTC](https://discourse.datamethods.org/t/quality-of-remdesivir-trials/3881/29 "2020-11-12T23:01:13Z")

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I applaud the effort, although looking at this study my inner @f2harrell voice would point out [issues with the dichotomization of variables](https://discourse.datamethods.org/t/categorizing-continuous-variables/3402) (e.g., age \< 65 vs \>65), variable selection based on p \< 0.1 on univariate analysis ([that is a big no-no](https://pubmed.ncbi.nlm.nih.gov/29292533/)), and [using changes from baseline](https://discourse.datamethods.org/t/reporting-both-baseline-adjusted-effect-and-change-from-baseline-group-estimates/1846).

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