# RCT with missing follow-up outcomes: ANCOVA + MI vs Mixed-Effects Modelling?

**URL:** <https://discourse.datamethods.org/t/rct-with-missing-follow-up-outcomes-ancova-mi-vs-mixed-effects-modelling/5809>\
**Category:** general\
**Tags:** strategy, missing-data, rct\
**Created:** [July 6, 2022, 6:54am UTC](https://discourse.datamethods.org/t/rct-with-missing-follow-up-outcomes-ancova-mi-vs-mixed-effects-modelling/5809 "2022-07-06T06:54:35Z")\
**Posts on this page:** 1\
**Showing post:** 3

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**Author:** ![MSchwartz](https://discourse.datamethods.org/user_avatar/discourse.datamethods.org/mschwartz/32/2579_2.png) [@MSchwartz](https://discourse.datamethods.org/u/MSchwartz)\
**Post date:** [July 6, 2022, 3:43pm UTC](https://discourse.datamethods.org/t/rct-with-missing-follow-up-outcomes-ancova-mi-vs-mixed-effects-modelling/5809/3 "2022-07-06T15:43:12Z")

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Hi,

In addition to Frank’s reply above, you might find a recent thread in this forum of interest:

[Linear mixed model for 3 time points](https://discourse.datamethods.org/t/linear-mixed-model-for-3-time-points/5753)

There is a fair amount of discussion there regarding mixed effects models, specifically with two post-baseline timepoints.

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