# \#added-value

**URL:** https://discourse.datamethods.org/tag/added-value/88.md

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## [Comparing 2 biomarkers using restricted cubic splines - how-to, interpretation, model building](https://discourse.datamethods.org/t/comparing-2-biomarkers-using-restricted-cubic-splines-how-to-interpretation-model-building/663)

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**Author:** [@tomkaier](https://discourse.datamethods.org/u/tomkaier)\
**Replies:** 63\
**Last updated:** [December 17, 2018, 5:18pm UTC](https://discourse.datamethods.org/t/comparing-2-biomarkers-using-restricted-cubic-splines-how-to-interpretation-model-building/663 "2018-12-17T17:18:30Z")

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Hi everyone, inspired by the topic started by @kiwiskiNZ - see Troponin, its use and misuse to rule-out and rule-in heart attacks - #34 by chapdoc1 - I had a question as to how you would go about analysing cardiac bioma…