sure: https://journals.sagepub.com/eprint/86qEsHtBJHuZjNRQyr7H/full maybe we should delete the link later, i’m not sure how seriously to take the warning re posting the link on a message board
i see. Rogers and Pocock had a nice paper on joint frailty model where they comapred it to alternatives: Rogers & Pocock et al. joint frailty There will be a lot of chat in the paper that isn’t of interest but skip to section “Jointly Modelling Recurrent Heart Failure Hospitalisations and Cardiovascular Death”
re “I also need to know which events you had so I can add up costs”, we did soemthing similar here: CQO paper, because emergency department visits and hospitalisations incur different costs, thus we treated them as separate but correlated events, using multivariate random effects [edit: and with a joint frailty for death as per rogers & pocock]
there’s also the multi-state approach you mentioned, it has been discussed on the message board before: Question on modeling repeated outcomes among single patients
i have similar data but i am thinking i’ll take the approach described by @f2harrell. I have some reading to do but can maybe update later. Like you we have a lot of data, the denominator is in fact so large that censoring overwhlems everything and i may be forced to take a less interesting route or combine events …