Hello,

In a retrospective clinical study.

In linear regression (generalized least squares model) a correlation coefficient of -0.34 is it weak or moderate ?

Appreciate your comments

# Correlation coefficient

**Josie24**#1

**RonanConroy**#2

Without knowing what your study is, what the correlation is measuring, why you did the study in the first place itâ€™s impossible to tell. Itâ€™s a bit like asking us if â‚¬34 is good value or cheap.

Please tell us a little more about what you are doing, and why you want to know. I am suspicious of what are often called tee-shirt sizes. If a correlation of â€“0Â·34 doesnâ€™t mean anything to a person, then calling it â€śweakâ€ť or â€śmoderateâ€ť wonâ€™t really help.

In general, I dislike correlations. They are poor measures of effect size because they lose the original variable metrics. And they are hard to explain in plain language (or impossible, as in the case of Spearmanâ€™s *rho*) â€“ hence the recourse to tee-shirt sizes, I believe.

So, more detail please!

Exactly. There is not nearly enough detail in the original post to answer this question. Please give some more information so we can better help you.

**Jochen**#4

In addition to the very correct answers above, Iâ€™d like to stress that this value(-0.34) is just a point-estimate. There is some uncertainty accosiated with this value, which might be given by a confidence interval.This intervalcould range from -0.9 to +0.6, in which case really nothing much could be stated about the strength of the relationship, even if one could connect the numbers (like -0.34) to some degree of practical relevance.

I completely subscribe to Ronans statement that correlations are poor(I would say almost useless) measures.

**f2harrell**#5

I agree with everything thatâ€™s been said. I do tend to use correlation coefficients when Iâ€™m in a hurry, or for computing sample sizes need to study relationships. For example n=400 is needed to estimate r with a margin of error of Â± 0.1 with 0.95 â€śconfidenceâ€ť.

**RGNewcombe**#6

Is a correlation coefficient of -0.34 weak or moderate? I fully take on board the criticisms previous respondents have raised. Nevertheless, the strength of quoting a correlation-type measure is that it is the nearest weâ€™ll ever get to a one-size-fits-all scale-free measure of effect size. Especially if you make it non-parametric - enabling (informal) comparison of strength of effect for a wide range of pairwise associations.

The sign is always important to note carefully - here inverse - we always need to check carefully that the direction of any association is in line with what we would logically expect.

And the absolute magnitude, 0.34. In one sense, this is a very weak correlation - one of the variables is capable of explaining away 0.34*0.34 or less than one-eighth of the variation of the other. On the other hand, as correlations in epidemiology go, itâ€™s much stronger than most correlations we normally encounter. Correlations tend to be low simply because most variables are influenced by numerous other variables.

**f2harrell**#7

The wish to add labels such as â€śsignificantâ€ť, â€śstrongâ€ť, â€śmoderateâ€ť, â€śweakâ€ť, or a medical diagnoses (â€śdiabetesâ€ť instead of just stating the severity of diabetes) does much more harm than good IMHO.

**Josie24**#8

I appreciate all of your responses. I have been working night shifts for a whole week, thus my delay in responding. Iâ€™ll provode

more info as soon as I can.

**jroon**#9

Donâ€™t forget the datasaurus!

https://cran.r-project.org/web/packages/datasauRus/vignettes/Datasaurus.html

The 13 distributions shown on that page all have almost the same summary statistics including the x-y correlation coefficient. And so you see interpreting a correlation coefficient by itself is not wise!

**RonanConroy**#10

The trouble is you cannot â€śjust state the severityâ€ť of diabetes, or cholesterol, or blood pressure. Many biological parameters that vary on a continuous scale have no definable threshold. Risk of adverse events rises with each unit of cholesterol, with each unit of blood glucose.

Furthermore, the severity of a given cholesterol â€“ 6 iu/L, say â€“ depends on other factors â€“ in the context of a 65-year-old with an SBP of 160 and a life of smoking, itâ€™s associated with a substantial risk of a cardiovascular event. But in a young, nonsmoking woman with an SBP of 110, itâ€™s of no account.

There is, I think, a problem underlying your problem, which is that itâ€™s hard to wean clinicians away from a fixation on managing individual risk factors and to get them to manage total risk.

**f2harrell**#11

The lack of a definable threshold is more reason to pursue this. I wasnâ€™t speaking of severity in terms of impact but rather severity with regard to the isolated disease process, e.g., for hypertension what is the untreated SBP, or for diabetes the HbA1c (if you donâ€™t have more details including various glucose levels).