Development of prediction models for multi-omic data: Is this a valid approach to follow?

I posted some references to older but still relevant papers, in these threads:

  1. Bayesian Model Averaging:
    RMS Describing, Resampling, Validating, and Simplifying the Model - #63 by R_cubed

  2. Frequentist Model Averaging:
    Should one derive risk difference from the odds ratio? - #447 by R_cubed