I’m working with a longitudinal dataset of patients divided into two cohorts:

Cohort 1:

- Tested at 21 days (baseline), 28, 35, and 42 days.

Cohort 2:

- Tested at 35 days (baseline), 42, 49, and 56 days.

Is this suitable for a first-order Markov model even though patients were not tested at the exact time points and each cohort has a different baseline time point?