i really like this topic and will read your paper. Another application, suggested on this message board, is hba1c and hypoglycemia: Is it reasonable to adjust for a post-baseline covariate? and i linked to this recent paper: An Application of Joint Modeling of Longitudinal and Time-to-Event Data in the Pittsburgh Epidemiology of Diabetes Complications Study
some have used a ‘global rank composite’ as the primary outcome of an RCT, combining survival outcomes and a biomarker. I’m not sure if anyone has done it, but i think it would be worthwhile comparing the performance of a global rank and a joint model … actually, i think someone did it in ALS