I can’t remember where I found it (probably one of Frank’s reference lists), but this paper on risk prediction as preferable to diagnosis (classification) is really where clinical care needs to go, especially with regulators insisting on health systems that get payments engage in financial risk taking for the care provided.
That, in turn, implies that quality assurance and improvement would be involved in the development and implementation of risk prediction (and reduction) models, instead of checklists based on arbitrary dichotomies.
Addendum: A related article on risk adjusted payments for primary care. These are the types of models doctors, nurses, and other professionals on the front lines need. A critical point – educating these people on when the model is not applicable will be critical if outcomes are to be improved.