95% CI for proportional meta-analysis to be outside the 0-1 range

[R_cubed]

@trumanfrancis

When you have such significant heterogeneity it is interesting to explore what might be causing this.

Much of what @llynn wrote in this thread would also apply to psychiatric syndromes, but it depends upon the specific question asked.

The End of the "Syndrome" in Critical Care

I have been periodically discussing the state of RCT in critical care. While there have been but few on-line comments, I have been encouraged by the off-line comments and approvals of that which I am trying to teach here. This work comes from 40 years in the ICU watching the evolution of the science and I speak primarily to the young who may still be developing an overarching cognitive construct of critical care science. This is the evolution I observed over 40yrs: The emergence of “thresh…