I am in need of statistical advice. My aim is “To derive waist circumference cut-off values predictive of metabolic syndrome among ART-experienced and naïve patients”.
Metabolic syndrome is defined as having 3 or more of the following characteristics: raised Blood pressure, waist circumference, fasting blood sugar, triglycerides and reduced high-density lipoprotein. Currently, there are no abnormal values of waist circumference specific for black Africa, the one used is based on Europid population which I feel might be different.
If I want to answer that objective, does it mean I need to omit waist circumference in the definition of metabolic syndrome and just leave the four characteristics? or I can still include and find the best predictive values of waist circumference for metabolic syndrome.
Maybe I need to first find the normal and abnormal ranges of waist circumference among our population (note that in Africa we still use the Europid values- no data so far specific for our setting) and see how best they can predict MS as compared to that Europid currently being used.
I will really appreciate your guidance, I am kind of confused about which route to take.