The End of the "Syndrome" in Critical Care

[llynn]

The methods of PathologicalConsensus are simple.. The consensus group is free to update and change the measurements for RCT..

Don’t miss the sister discussion of a new update at

What is a fake measurement tool and how are they used in RCT

I have linked an article below published this month. This provides more evidence that the measurement tools used for critical care RCT esp. for sepsis and mortality are often fake. Those who have studied this issue did not need more evidence but perhaps if enough of these studies are published the perceived bright star of SOFA will fade (as SIRS has faded). This study is no surprise given there has not been a single reproducibly positive sepsis RCT for 30 yrs. Now fake is a harsh word and I d…

The Sequential Organ Failure Assessment (SOFA) Score: has the time come for...

Changing SOFA would presumably change the criteria for RCT of the “Synthetic Syndrome” of sepsis which is based on the old 1996 SOFA. .Here you see how variable the synthetic syndrome actually is and why the RCT are not reproducible.

Not only does the guessed set of thresholds capture a variable mix of diseases but the guessed set itself also changes at the will of the consensus group..

RCT reproducibility using guesses (especially freely changeable guesses) as measurements should not be expected..