treatment comparison

general General issues, logistics, and ethics related to treatment comparison studies. interpret Statistical interpretation of particular trials and studies comparing treatments. Some of the issues of interest include clinical vs. statistical significance, interpretation errors, and the absence of evidence is not evidence of absence error. design Designs for particular treatment comparison studies, both randomized and observational observational Methods for comparison of nonrandomized treatments, including propensity score and instrumental variables approaches

Topic	Replies	Views	Activity
About the treatment comparison category treatment comparison tx-compare	0	2681	July 14, 2018
Use of conditional estimands in regulatory settings interpret rct	2	148	April 29, 2025
Sample Size in crossover trials design design , power	4	918	August 29, 2024
Optimal timing for rescue strategy after repeated failed treatment attempts observational design	3	879	April 18, 2024
Interpreting Survival Probability in Relation to 'Number at Risk' and Median Follow-Up Times interpret survival-analysis , interpretation	2	1780	October 3, 2023
Interim Analysis Plan for Observational Studies treatment comparison design	3	1944	August 16, 2023
Change of study design of an ongoing clinical trial design bayes , sap	4	2499	June 9, 2023
Which to make as the primary analysis general design , rct	1	2669	July 25, 2022
Logistics of treatment effect estimation with interim analyses design design , rct , sequential	1	1651	June 1, 2022
How to estimate the sample size when the variance of the outcome is unknown in the population treatment comparison	2	1534	April 21, 2022
One-Sample Log-Rank Test general	1	3306	July 8, 2021
Clinical Trial Outcomes Interrupted by Other Outcomes design multiple-endpoints	19	9329	June 13, 2021
Multiplicity in clinical trials with hierarchical strategy interpret multiplicity , rct	2	6981	December 30, 2020
Query regarding interquartile range effects in summary plots interpret rms	1	3238	September 5, 2020
Modeling for Observational Treatment Comparisons observational propensity	0	2384	May 29, 2020
Investigate parallel observational cohort or leave alone? design generalizability , epi	0	2090	May 18, 2020
French target trial using obs data of HCQ vs not in SARS-CoV-2 infection observational interpretation , design , covid-19	0	3246	April 15, 2020
Subgroup Interaction design interaction , subgroup	2	4269	April 8, 2020
RCT generalizability and interactions with treatment design generalizability , interaction , rct	8	5392	March 10, 2020
Dexamethasone treatment for the acute respiratory distress syndrome observational meta-analysis	1	3080	February 21, 2020
Crude OR vs adjusted OR treatment comparison	2	7014	November 27, 2019
Interpretation of RCTs: Evidence vs. Hypothesis Generating interpret decision-making	8	5793	November 21, 2019
Which error is more beneficial to the society? interpret	13	7337	August 15, 2019
The pointlessness of small effects in epidemiology treatment comparison design	17	6848	July 4, 2019
Methods for comparing healthcare costs between two treatment regimens in a non-CT setting? observational cost	2	2835	June 11, 2019
Propensity score matching with missing data observational	5	9323	June 11, 2019
Has this JAMA Patient Page at last threaded the needle of explaining p-values? general	15	5580	December 4, 2018
Proposal for a different way to analyze multivariate treatment safety outcomes interpret rct , safety , logistic-regression , multivariate	0	4419	November 11, 2018
What does interaction between treatment and propensity to treat signify? observational propensity , data-reduction	10	9775	October 18, 2018
Evidence grading - weight causal inference from retrospective v prospective data capture? observational	1	2883	September 6, 2018