treatment comparison

general General issues, logistics, and ethics related to treatment comparison studies. interpret Statistical interpretation of particular trials and studies comparing treatments. Some of the issues of interest include clinical vs. statistical significance, interpretation errors, and the absence of evidence is not evidence of absence error. design Designs for particular treatment comparison studies, both randomized and observational observational Methods for comparison of nonrandomized treatments, including propensity score and instrumental variables approaches

Topic	Replies	Views	Activity
About the treatment comparison category treatment comparison tx-compare	0	2675	July 14, 2018
Use of conditional estimands in regulatory settings interpret rct	2	68	April 29, 2025
Sample Size in crossover trials design design , power	4	907	August 29, 2024
Optimal timing for rescue strategy after repeated failed treatment attempts observational design	3	856	April 18, 2024
Interpreting Survival Probability in Relation to 'Number at Risk' and Median Follow-Up Times interpret survival-analysis , interpretation	2	1553	October 3, 2023
Interim Analysis Plan for Observational Studies treatment comparison design	3	1852	August 16, 2023
Change of study design of an ongoing clinical trial design bayes , sap	4	2398	June 9, 2023
Which to make as the primary analysis general design , rct	1	2655	July 25, 2022
Logistics of treatment effect estimation with interim analyses design design , rct , sequential	1	1643	June 1, 2022
How to estimate the sample size when the variance of the outcome is unknown in the population treatment comparison	2	1507	April 21, 2022
One-Sample Log-Rank Test general	1	3258	July 8, 2021
Clinical Trial Outcomes Interrupted by Other Outcomes design multiple-endpoints	19	9261	June 13, 2021
Multiplicity in clinical trials with hierarchical strategy interpret multiplicity , rct	2	6873	December 30, 2020
Query regarding interquartile range effects in summary plots interpret rms	1	3216	September 5, 2020
Modeling for Observational Treatment Comparisons observational propensity	0	2358	May 29, 2020
Investigate parallel observational cohort or leave alone? design generalizability , epi	0	2087	May 18, 2020
French target trial using obs data of HCQ vs not in SARS-CoV-2 infection observational interpretation , design , covid-19	0	3240	April 15, 2020
Subgroup Interaction design interaction , subgroup	2	4248	April 8, 2020
RCT generalizability and interactions with treatment design generalizability , interaction , rct	8	5363	March 10, 2020
Dexamethasone treatment for the acute respiratory distress syndrome observational meta-analysis	1	3055	February 21, 2020
Crude OR vs adjusted OR treatment comparison	2	6939	November 27, 2019
Interpretation of RCTs: Evidence vs. Hypothesis Generating interpret decision-making	8	5772	November 21, 2019
Which error is more beneficial to the society? interpret	13	7291	August 15, 2019
The pointlessness of small effects in epidemiology treatment comparison design	17	6780	July 4, 2019
Methods for comparing healthcare costs between two treatment regimens in a non-CT setting? observational cost	2	2818	June 11, 2019
Propensity score matching with missing data observational	5	9244	June 11, 2019
Has this JAMA Patient Page at last threaded the needle of explaining p-values? general	15	5511	December 4, 2018
Proposal for a different way to analyze multivariate treatment safety outcomes interpret rct , safety , logistic-regression , multivariate	0	4415	November 11, 2018
What does interaction between treatment and propensity to treat signify? observational propensity , data-reduction	10	9644	October 18, 2018
Evidence grading - weight causal inference from retrospective v prospective data capture? observational	1	2856	September 6, 2018