data analysis


uncertainty Quantifying uncertainty, displaying uncertainty, estimation of uncertainty, incorporation of uncertainty into decision making, etc. This includes but is not limited to confidence intervals, standard errors, Bayesian credible intervals, and sources of uncertainty. data problems statistical approaches dealing with missing data and measurement error data reduction data reduction (principal components, etc.), clustering, unsupervised learning model validation model validation and interpretation accuracy accuracy and information measures, discriminaton, calibration formal statistical tests and inference bayes Bayesian data analysis, modeling, inference descriptive descriptive and exploratory data analysis, hypothesis generating more than confirmatory analysis probability Probability theory, meaning, and application exclusive of statistical tests, etc. generalizability Generalizability of studies and statistical inferences, sample representativeness, target population comparative methods comparative performance of statistical analysis methods and predictive modeling approaches machine learning machine learning, exclusive of traditional statistical models causal inference Methods and approaches to causal inference modeling strategy General model specification issues, nonlinearities, interactions and heterogeneity of treatment effect, avoiding categorization, how to sequence multiple steps (which may involve multiple imputation and data reduction) variable selection Selection of predictive features in multivariable modeling, one-at-a-time screening of variables, and the cost of feature selection compared to using fuller models, possibly with penalization (shrinkage; regularization). models Formulation, parameter estimation, and interpretation of specific statistical models
Topic Replies Activity
About the data analysis category 2 January 21, 2019
How to handle large number of observations below LLOQ 2 November 19, 2019
Competing risk for AFT models in R 4 November 18, 2019
Conceptual question about survival analysis vs logistic regression: when is one more appropriate than the other? 7 November 18, 2019
How to get new statistical methods to be used in practice 2 November 18, 2019
How to determine the p value cutoff for unvariate regression analysis to be included in multivariate analysis 3 November 17, 2019
Comparing pre/post variance by cluster 5 November 16, 2019
Restricted mean survival time and comparing treatments under non-proportional hazards 2 November 15, 2019
Marginal vs conditional (Mixed) models used in Joint model analysis. The SPRINT trial controversy 9 November 14, 2019
A statistical misadventure leading to retraction 7 November 13, 2019
Multiplicity Adjustments in Bayesian Analysis 8 November 8, 2019
TSSA (tree-structured survival analysis) in R 4 November 6, 2019
"Observed Power" and other "Power" Issues 71 November 2, 2019
Best method to derive preliminary gene expression signature from a published set of prognostic genes (with Cox scores) 6 October 25, 2019
Examples of solid causal inferences from purely observational data 6 May 13, 2019
Adherence adjustment in randomized trials is possible, here's why 5 July 9, 2019
Comparison of prevalence over years 1 October 14, 2019
RCT ceiling effects and high drop off rate 7 October 14, 2019
Does data-based variable reduction lead to confounding? 10 October 12, 2019
Multivariable model with variables missing in select patient subsets 11 October 9, 2019
Assessing variable importance over time 6 October 7, 2019
Simulating survival data to evaluate statistical power for survival analysis 2 October 6, 2019
Statistically Efficient Ways to Quantify Added Predictive Value of New Measurements 11 October 3, 2019
Reference Collection to push back against "Common Statistical Myths" 32 September 14, 2019
Maximum number of predictors in pooled logistic regression 8 October 2, 2019
Conditional Independence Assumption 3 September 30, 2019
Use of synthetic data in model development 4 September 30, 2019
Information criteria vs cross validation 4 September 29, 2019
Calibration curve for pooled logistic regression 1 September 28, 2019
Discussion: Why Bayes for Clinical Trials 7 September 24, 2019