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FDA Draft Guidance: Use of Bayesian Methodology in Clinical Trials of Drug and Biological Products
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10
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535
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March 2, 2026
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One-sided significance threshold of less than 0.1 in Phase 2 clinical trial
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7
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108
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February 25, 2026
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Statin-related side effects: the recent Lancet publication is biased toward false-negatives
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19
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446
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February 19, 2026
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Bootstrapped variable selection in the presence of competing risk
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7
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120
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January 12, 2026
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The growing interest in integrating causal inference and Design Theory
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7
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221
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January 6, 2026
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Should causal modeling be a required part of a NIH grant applications?
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1
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108
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December 17, 2025
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Randomized non-comparative trials: an oxymoron?
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73
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4460
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December 15, 2025
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Cause-Agnostic RCT (CAR)
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9
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442
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December 12, 2025
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A High-Fiber Plant-Based Diet in Myeloma Precursor Disorders – Results from the 2 NUTRIVENTION Clinical Trial and Preclinical Vk*MYC Model
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2
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96
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December 11, 2025
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MICE Imputation Models
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10
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420
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December 6, 2025
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NEJM Trial - proportional hazard assumption
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12
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371
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December 1, 2025
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The Design Theory /Causal Inference Divide Explained by the Position of U
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2
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147
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November 28, 2025
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Rarity Roulette: A simulator for estimating hypothetical outcomes spreads for mass screenings
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2
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92
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November 20, 2025
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Individual response
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266
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49052
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November 17, 2025
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When and why (not) to worry about the PO assumption
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4
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649
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October 9, 2025
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Comparing multiple groups to a reference group
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7
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215
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October 6, 2025
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Bayesian Clinical Trials: Interview with Frank Harrell
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0
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234
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September 18, 2025
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Estimating the probability of neonatal sepsis with plug-in incidence
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6
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140
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September 11, 2025
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Fine-Gray vs Cause-Specific Cox Regression
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0
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136
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September 11, 2025
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Sample Size Calculation for a 2x2 Factorial RCT
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6
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307
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September 3, 2025
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Table 2 Fallacy?: Association of 5α-Reductase Inhibitors With Dementia, Depression, and Suicide
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32
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4256
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August 12, 2025
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Illogic of Weighting While Estimating Model Parameters
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13
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827
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August 11, 2025
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Statistical Process Control and Experimental Design
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9
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412
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May 13, 2025
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Challenges in determining meaningful between group differences of surgery vs non-surgical treatment
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12
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783
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May 9, 2025
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Why the Non-Reproducibility of Acute Care RCT? The CAP studies
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6
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203
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May 8, 2025
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Should I Exclude Patients Based on Treatment Criteria?
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4
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92
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April 29, 2025
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Reanalyzing MERIT design using Julia + recent numerical algorithms
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2
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184
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April 28, 2025
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Decision analysis calculations
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17
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475
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April 27, 2025
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Factorial trial with interest in individual contrasts
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1
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53
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April 26, 2025
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CONSORT 2025 RCT standards document
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2
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191
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April 25, 2025
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